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Gokhan Hotamisligil (Chair, Department of Genetics and Complex Diseases, Harvard School of Public Health):
"Sugar and Fat: The Sweet and Sour Metabolic Story of Modern Humans"

Monday, April 12, 2004, 4:00–5:00 PM EST

Bartos Theatre, MIT Media Lab (E15)

Hotamisligil's lab studies the molecular mechanisms of metabolic diseases which represent the biggest risk for modern humanity and affect an increasing and alarmingly large proportion of the global population. To expedite effective translation of this to preventive and therapeutic avenues for human disease, interdisciplinary studies encompassing basic molecular, cellular and genetic research; detection systems, population-based genetics and genomics; biostatistics and information sciences; epidemiology; nutrition; clinical translation; and social, policy and behavioral aspects are planned. An important feature of such an initiative is the development of advanced detection systems and "point of care" micro-scale devices that would allow effective data collection from free-living individuals as well as experimental models. With these, we hope to establish the foundation for an operational concept of "molecules to society" to address this important global biomedical threat to public health.

David Mosley: "Synthetic Biology: Progess in Merging Nanoparticles and Proteins"

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