Research
Biomechatronics

Enhancing human physical capability
Research
Conformable Decoders

Converting the patterns of nature and the human body into beneficial signals and energy
Research
Molecular Machines

Engineering at the limits of complexity with molecular-scale parts
Archived
Research
Health 0.0

Health 0.0
Archived
Project Research

Artificial Intelligence and Machine Learning in Clinical Development: A Translational Perspective

Technical summary: Future of clinical development is on the verge of a major transformation due to convergence of large new digital data so…
Archived
Archived
Project Research

Digital Clinical Trials with Novel Machine Learning and AI Architectures

Dr. Shah was an invited speaker and a contributor at The National Cancer Policy Forum developed workshop series at the The National Academi…
Archived
Archived
Project Research

Self-Learning AI Model Learns from Patient Data to Design Novel Clinical Trials

Technical summaryUnstructured learning problems without well-defined rewards are unsuitable for current reinforcement learning (RL) approac…
Archived
Archived
Project Research

Deep Learning to Develop and Analyze Computational Hematoxylin and Eosin Staining of Tissue Images for Digital Biopsies

Staining of tissues sections using chemical and biological dyes has been used for over a century for visualizing various tissue types and m…
Archived
Archived
Project Research

Research Area | Rapid Fabrication and Integration of Medical Devices and Technologies

Dr. Shah and his research lab at MIT has significant expertise and motivation to bring problems from the clinic and society into the labora…
Archived
Archived
Project Research

Research Area | Emergent Neural Networks to Redesign Clinical Testing of Medicines and Learning from Real World Evidence

Research studies led by Dr. Shah, in collaboration with the United States Food and Drug Administration (FDA),  have develope…
Archived
Article Research

Canan Dagdeviren wants more women in STEM to “Not give up”

“That’s one thing I always tell my female students.”
Project Research

Non-full-length G protein-coupled receptors: An unexpected discovery may lead to design new molecular devices

It was believed that functionalities of G protein-coupled receptors (GPCRs) require full-length sequences which are negated by residue dele…
Article Research

Truncated immune system receptors may regulate cellular activity

Unexpected findings in chemokine receptors once believed to be non-functional open up new fields of scientific inquiry.
Project Research

ORBIT (Olfactory Response Baseline Identification Test)

I am currently developing a new approach in conducting sensory examinations via the Olfactory Response Baseline Identification Test (O.R.B.…
Publication Research

Counterpoint: Artificial legs do not make artificially fast running speeds possible

R. Kram, A. M. Grabowski, C. P. McGowan, M. B. Brown, and H. M. Herr. Counterpoint: Artificial legs do not make artificially fast running speeds possible, Journal of Applied Physiology, vol. 108, no. 4, pp. 1012–1014, Apr. 2010.
Publication Research

Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series

D. Hill and H. M. Herr. Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013.
Publication Research

The fastest runner on artificial legs: Different limbs similar function?

P. G. Weyand, M. W. Bundle, C. P. McGowan, A. Grabowski, M. B. Brown, R. Kram, and H. Herr. The fastest runner on artificial legs: Different limbs, similar function?, Journal of Applied Physiology, vol. 107, no. 3, pp. 903–911, Sep. 2009.
Publication Research

Leg stiffness of sprinters using running-specific prostheses

C. P. McGowan, A. M. Grabowski, W. J. McDermott, H. M. Herr, and R. Kram. Leg stiffness of sprinters using running-specific prostheses, Journal of the Royal Society Interface, vol. 9, no. 73, pp. 1975-1982, 2012.
Publication Research

Bionic ankle-foot prosthesis normalizes walking gait for persons with leg amputation

H. M. Herr and A. M. Grabowski. Bionic ankle-foot prosthesis normalizes walking gait for persons with leg amputation, Proceedings of the Royal Society B, vol. 279, no. 1728, pp. 457–464, Feb. 2012.
Publication Research

Running-specific prostheses limit ground-force during sprinting

A. M. Grabowski, C. P. McGowan, W. J. McDermott, M. T. Beale, R. Kram, and H. M. Herr. Running-specific prostheses limit ground-force during sprinting, Biology Letters, vol. 6, no. 2, pp. 201-204, 2010.