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City Science researchers are developing a slew of tangible and digital platforms dedicated to solving spatial design and urban planning cha…
What if clinicians could place tiny electronic chips inside the brain without the need for any surgery but with a simple injection in the a…
Nano-Implants for Wireless Brain Interfacing
Lyme disease is the most common vector-borne infection in North America. People are infected when bitten by ticks — and ticks usually becom…
CyberBiome is a programmable bio-digital organ, a wearable biosynthesis platform for personalized, on-demand production of therapeutics and…
Radical treatment for pain and neurodegenerative diseases
Facemasks are used to reduce exposure to viruses and other environmental hazards such as air pollution, and integrating wearable electronic…
Precise neurostimulation can revolutionize therapies for neurological disorders. Electrode-based stimulation devices face challenges in ach…
MicroPET is an autonomous payload for enzymatic reactions and microbial cultivation with fully programmable serial passaging and sampl…
RNA is a fundamental biomolecule that stands at the intersection of modern biology and the origins of life. It carries genetic instruc…
Recent advances in clinical AI have enabled remarkable progress across many clinical domains. However, existing benchmarks and models are p…
COVID-19 has over only a few short months resulted in the deaths of >400,000 people worldwide (as of mid-June 2020) and has forced many …
Biplanar fluoroscopy (BiFlo) enables three-dimensional bone kinematics analysis using x-ray videos and bone geometry from segmented CT. Hin…
Ultrasound is widely used for tissue imaging such as breast cancer diagnosis; however, fundamental challenges limit…
Ultrasound-induced transdermal drug delivery (sonophoresis) has long lingered in the by-lanes of academic and industrial research, and has …
For details and recent updates visit: https://web.mit.edu/deblina-sarkar/Nanoelectronics has the potential to enable radical too…
This project focuses on developing and integrating new powered prosthetic limbs, sensor systems, and surgical technologies to restore neura…
Existing upper extremity prosthesis controllers have limited functionality and place high cognitive demands on users, both of which contrib…
How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drives?…
AbstractDevices that facilitate nonverbal communication typically require high computational loads or have rigid and bulky form factors&nbs…
A Distance Learning Model for Global Laboratory-Based Synthetic Biology Education Synthetic Biology ( SynBio) tools hold the…
A world in which thousands of people can construct and release autonomous biological agents is unlikely to flourishProfessor Kevin Esvelt, …
Recent advances in medications for neurodegenerative disorders are expanding opportunities for improving the debilitating symptoms suffered…
FlowIO is the first fully-integrated and truly general-purpose, miniature pneumatics development platform for control, actuation, and sensi…
Improvements in ingestible electronics with the capacity to sense physiological and pathophysiological states have transformed the standard…
Nearly all classes of wearable and implantable biomedical devices depend on battery power for continuous operation. However, the life span …
The rapid advancement of electronic devices and fabrication technologies has further promoted the field of wearables and smart textiles. Ho…
Humanity has harnessed evolution to sculpt domesticated animals, crops, and molecules, but the process remains a black box. Which combinati…
Lower-extremity amputees face a series of potentially serious post-operative complications. Among these are increased risk of further amput…
Humans can accurately sense the position, speed, and torque of their limbs, even with their eyes shut. This sense, known as proprioception,…
The human body produces a variety of different electrophysiological signals from brain-waves (EEG) to the electrical activity of the heart …
Academic research groups, especially the ones directed by new junior faculty, are under pressure to produce high-quality work timely while …
During the gait cycle, the human ankle complex serves as a primary power generator while simultaneously stabilizing the entire limb. These …
This research track focuses on the use of computational (and experimental) techniques to understand the biomechanical behavior of human tis…
The design of next-generation bionic ankles and knees aims to improve bionic actuators on all metrics: range of motion, power density, band…
Recent advancements in orthopedic implants have made way for a new generation of bionic limbs that attach directly to the skeleton. Leverag…
Lower-extremity amputation surgery has not seen significant change since the Civil War. This research is focused on the development of nove…
The human ankle provides a significant amount of net positive work during the stance period of walking, especially at moderate to fast walk…
Recent advances in artificial limbs have resulted in the provision of powered ankle and knee function for lower extremity amputees and powe…
It was believed that functionalities of G protein-coupled receptors (GPCRs) require full-length sequences which are negated by residue dele…
Doze is an IoT enabled platform for personalized scent diffusion and on-skin drug delivery. Leveraging a hydrogel technology, the Doze syst…
Living Bits : Opportunities and Challenges for Integrating Living Microorganisms in Human-Computer InteractionThere are trillions of living…
Programmable CRISPR enzymes are powerful and versatile tools for genome editing. They, however, require a specific protospacer adjacent mot…
There are 20 chemokine receptors that bind their respective chemokines. It is not currently understood how these structurally similar recep…
The past two decades have seen unprecedented progress in the development of novel materials, form factors, and functionalities in neuroimp…
Plants can sense the environment, other living entities and regenerate, actuate or grow in response. Our interaction and communication…
Can a person look at a portable display, click on a few buttons, and recover his or her refractive condition? Our optometry solution combin…
In the United States, there are an estimated 1.7 million people living with amputation, with that number expected to double by 2050. Compl…
Who should decide whether, when, and how to alter the environment? These are hard questions, especially when the decisions will impact peop…
We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifying…