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We have pioneered the development of fully genetically encoded reagents that, when targeted to specific cells, enable their physiology to...
City Science researchers are developing a slew of tangible and digital platforms dedicated to solving spatial design and urban planning c...
Real World Data (RWD) and Real World Evidence (RWE) are playing an increasing role in healthcare decisions. FDA and medical product devel...
Virtual and augmented reality headsets are unique as they have access to our facial area, an area that presents an excellent opportunity ...
This project seeks to examine the effects of altered gravity on an individual’s physiology during parabolic flight. Specifically, we will...
Recent advancements in orthopedic implants have made way for a new generation of bionic limbs that attach directly to the skeleton. Lever...
Two-dimensional radiographs are commonly used for evaluating sub-surface hard structures of teeth, but they have low sensitivity for earl...
Complex biological systems such as brain circuits are extended 3-D structures made out of nanoscale building blocks such as proteins, RNA...
Biplanar fluoroscopy (BiFlo) enables three-dimensional bone kinematics analysis using x-ray videos and bone geometry from segmented...
Recent advances in medications for neurodegenerative disorders are expanding opportunities for improving the debilitating symptoms suffer...
Continuous localized tissue monitoring and disease treatmentThe ability to continuously monitor physical patterns, such as pH in the...
Humans can accurately sense the position, speed, and torque of their limbs, even with their eyes shut. This sense, known as proprioceptio...
During the gait cycle, the human ankle complex serves as a primary power generator while simultaneously stabilizing the entire limb. Thes...
Lower-extremity amputees face a series of potentially serious post-operative complications. Among these are increased risk of further amp...
Improvements in ingestible electronics with the capacity to sense physiological and pathophysiological states have transformed the standa...
The brain is a three-dimensional, densely-wired circuit that computes via large sets of widely distributed neurons interacting at fast ti...
Paper diagnostics can be used for affordable and scalable biomarker detection. We propose new methods for stabilizing cellulose-based imm...
The development of biotechnologies since the era of recombinant DNA in the 1970s has occurred largely via the interaction of academic, in...
New technologies for recording neural activity, controlling neural activity, or building brain circuits, may be capable someday of servin...
We are providing our tools to the community, and also using them within our lab, to analyze how specific brain mechanisms (molecular, cel...
Nearly all classes of wearable and implantable biomedical devices depend on battery power for continuous operation. However, the life spa...
This research track focuses on the use of computational (and experimental) techniques to understand the biomechanical behavior of human t...
Lyme disease is the most common vector-borne infection in North America. People are infected when bitten by ticks; ticks are typically in...
Lower-extremity amputation surgery has not seen significant change since the Civil War. This research is focused on the development of no...
Recent advances in artificial limbs have resulted in the provision of powered ankle and knee function for lower extremity amputees and po...
The Synthetic Apiary proposes a new kind of environment, bridging urban and organismic scales by exploring one of the most important orga...
We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifyi...
Today’s health sensors (which monitor breathing, heartbeats, steps, etc.) require their users to wear them on their bodies. In contrast, ...
We collaborated with NIAS (National Institute of Agricultural Science) to genetically engineer silkworms to develop new kinds of silk for...
In the United States, there are an estimated 1.7 million people living with amputation, with that number expected to double by 2050. Comp...
Can a person look at a portable display, click on a few buttons, and recover his or her refractive condition? Our optometry solution comb...
How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drive...