Expansion Microscopy
New technique enables nanoscale-resolution microscopy of large biological specimens

In a new study published in Science, researchers from Ed Boyden's Synthetic Neurobiology group detail a new technique that allows them to use a polymer commonly found in diapers to physically enlarge brain tissue samples, enabling them to get high-resolution images of cellular activities. Learn more about how expansion microscopy works in this video, and explore the research and process in-depth at http://expansionmicroscopy.org/.

Details on expansion microscopy and interviews with the researchers can be found in the following press coverage:

The New York Times | Expansion Microscopy Stretches Limits of Conventional Microscopes

MIT News | MIT Team Enlarges Brain Samples, Making Them Easier to Image

WBUR | Diaper Power: Expanding Gel Could Help Scientists See Brain Workings

The Boston Globe | Instead of Zooming In, MIT Scientists Blow Up Brain Cells