Research Scientist - Optimization and Application of Expansion Microscopy, Synthetic Neurobiology

by Kelley Shepard

June 19, 2018


Job Description

Synthetic Neurobiology research group develops cutting-edge methods for methods for mapping the wiring and molecular composition of the brain. We are looking for a Research Scientist – optimization and application of expansion microscopy to help optimize and apply expansion microscopy, alone and in combination with novel in situ sequencing techniques, for the multimodal mapping of large numbers of biomolecules throughout diverse cells and tissues in healthy and disease states.


  • Help design, validate, and optimize the expansion microscopy and in situ sequencing protocols and help apply the resulting tools to normal and diseased brain tissue, and a diversity of other tissue types such as cancers and help analyze the data;
  • Write proposals to secure further research funding;
  • Write and present research results;
  • Collaborate and help research group team members and other collaborating students and postdocs on molecular mapping research;
  • Assist with lab coordination.



  • PhD in Biological Engineering, Biology, Neuroscience, or a related field;
  • At least one year of working experience with tissue handling, microscopy, and image data analysis;
  • Extensive expertise in molecular cloning, optical microscopy, and software skills (e.g., MATLAB programming, Linux systems, shell scripting) is required;
  • Excellent interpersonal skills and collaborative skills;
  • Demonstrated superb analytical/problem solving/critical thinking skills and judgment;
  • Attention to detail, superb organizational, documentation, communication, and time management skills required;
  • Able to work independently and self-motivated, one who is able to work as part of a tightly-knit team;
  • Demonstrated background and interest in neuroscience is required.


  • Experience in next-gen DNA sequencing and data analysis;
  • Demonstrated background and interest in neuroscience and/or cancer research.

Those who are interested should submit a resume and cover letter referencing job no. 16162 at; keyword is "Media Lab".

How to Apply

Find open positions at MIT by career area, location, full- or part-time, keyword and more.

More Job Opportunities