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Daisy Drives

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Kevin Esvelt | MIT Media Lab

by Chia Evers

April 3, 2019

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Daisy-chain gene drives for the alteration of local populations

Noble, Charleston, John Min, Jason Olejarz, Joanna Buchthal, Alejandro Chavez, Andrea L. Smidler, Erika A. DeBenedictis, George M. Church, Martin A. Nowak, and Kevin M. Esvelt. “Daisy-Chain Gene Drives for the Alteration of Local Populations.” Proceedings of the National Academy of Sciences, April 2, 2019, 201716358. https://doi.org/10.1073/pnas.1716358116.
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Keeping genetic engineering localized

In a paper published in PNAS, researchers at MIT and Harvard University describe a self-limiting gene drive system.
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This gene technology could change the world. Its maker isn’t sure it should.

How does one scientist deal with the potential ramifications of his own creation?
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Part 1: Gene Drive; Part 2: Gene Drive and Local Drive

iBiology features two introductory classes from CRISPR expert Kevin Esvelt, head of the Media Lab's Sculpting Evolution group.