Publication

Electrodermal Sleep Storm Activity as A Biomarker In Epilepsy Patient

Dec. 1, 2014

Groups

Kapur K., Thome-Souza S., Klehm J., Sarkis R., Nagarajan E., Jackson M., Rosalind W. Picard, Doshi C., Papadelis C., Dworetzky B., Reinsberger C., Loddenkemper T.

Abstract

Use of spontaneous electrodermal activity (EDA) sleep storms in epilepsy has been raised as a new tool to guide clinicians regarding to seizure lateralization. A storm is defined as clusters of EDA during sleep with 5 EDA/minute over 10 consecutive minutes. There is no data on EDA sleep storms in patients with epilepsy. We believe that EDA sleep storms could be a useful biomarker to correlate epilepsy characteristics with sympathetic nervous system activity. Thus, our objective was to analyze EDA sleep storms in epilepsy patients and correlate with patient and seizure demographics, MRI lesion, and EEG findings to delineate a better profile of storms in this population.

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