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Picard, Rosalind & Devinsky, Orrin & Dworetzky, Barbara & French, Jacqueline & Friedman, D. & Lai, M. & Loddenkemper, Tobias & Poh, M.-Z & Reinsberger, Claus & Sarkis, Rani & Surges, Rainer. (2015). The importance of measuring autonomic data in new epilepsy treatments. Epilepsy & Behavior. 46. 54-55. 10.1016/j.yebeh.2015.02.053.
Summary: Measuring autonomic data is important • Autonomic data measured from the skin reflects activation of deep brain circuits, while being comfortably and easily measured 24/7. • The size of autonomic disruption is significantly correlated with duration of PGES, providing an important candidate biomarker for SUDEP. • The accuracy of GTCS detection is improved using EDA • Significant EDA activation occurred in 86% of CPS, which may contribute to helping automate CPS detection. • Personalized autonomic patterns can be examined over time to objectively examine interactions with AED’s