Enhancing human physical capability

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MIT Media Lab

MIT Media Lab

Publication

Mechanoneural interfaces for bionic integration

Shu, T., Herrera-Arcos, G., Taylor, C.R. et al. Mechanoneural interfaces for bionic integration. Nat Rev Bioeng (2024). https://doi.org/10.1038/s44222-024-00151-y

Publication

Resting State Neurophysiology of Agonist-Antagonist Myoneural Interface in Persons with Transtibial Amputation

L. Chicos, D. Rangaprakash, R. Barry, H. Herr, Resting State Neurophysiology of Agonist-Antagonist Myoneural Interface in Persons with Transtibial Amputation. under review at Nature Communications Medicine. (2023).

Publication

Untethered muscle tracking using magnetomicrometry

Taylor CR, Yeon SH, Clark WH, Clarrissimeaux EG, O’Donnell MK, Roberts TJ and Herr HM (2022) Untethered muscle tracking using magnetomicrometry. Front. Bioeng. Biotechnol. 10:1010275. doi: 10.3389/fbioe.2022.1010275

Publication

Clinical viability of magnetic bead implants in muscle

Taylor CR, Clark WH, Clarrissimeaux EG, Yeon SH, Carty MJ, Lipsitz SR, Bronson RT, Roberts TJ and Herr HM (2022) Clinical viability of magnetic bead implants in muscle. Front. Bioeng. Biotechnol. 10:1010276. doi: 10.3389/fbioe.2022.1010276

Publication

Agonist-antagonist Muscle Strain in the Residual Limb Preserves Motor Control and Perception after Amputation

Song H, Israel EA, Gutierrez-Arango S, Teng AC, Srinivasan SS, Freed LE, Herr HM. Agonist-antagonist Muscle Strain in the Residual Limb Preserves Motor Control and Perception after Amputation. Communication Medicine (Lond). 2022 Aug 5;2:97. doi: 0.1038/s43856-022-00162-z PMID35942078; PMC9356003 2022 (Publisher Correction 2022 Sep 26;2:121. doi: 10.1038/s43856-022-00188-3).

Publication

Acquisition of Surface EMG Using Flexible and Low-Profile Electrodes for Lower Extremity Neuroprosthetic Control

Yeon, Seong Ho, et al. "Acquisition of surface emg using flexible and low-profile electrodes for lower extremity neuroprosthetic control." IEEE Transactions on Medical Robotics and Bionics 3.3 (2021): 563-572.

Publication

A Virtual Muscle Model of the Arm for EMG-Driven Control of Prostheses

Publication

The Agonist-antagonist Myoneural Interface

Herr HM, Carty MJ. The Agonist-antagonist Myoneural Interface. Tech Orthop. 2021 Dec;36(4):337-344. doi: 10.1097/bto.0000000000000552. PMID: 34866774; PMCID: PMC8630671.

Publication

Magnetomicrometry

C. R. Taylor, S. S. Srinivasan, S. H. Yeon, M. K. O'Donnell, T. J. Roberts, H. M. Herr, Magnetomicrometry, Sci.Robot. 6, eabg0656 (2021), DOI: 10.1126/scirobotics.abg0656

Publication

The Agonist-Antagonist Myoneural Interface

Carty, M.J. and Herr, H.M. The Agonist-Antagonist Myoneural Interface. Hand Clinics. 2021 Aug;37(3):435-445. doi: 10.1016/j.hcl.2021.04.006. https://pubmed.ncbi.nlm.nih.gov/34253316/

Publication

Acquisition of Surface EMG Using Flexible and Low-Profile Electrodes for Lower Extremity Neuroprosthetic Control

Yeon SH, Shu T, Song H, Hsieh TH, Qiao J, Rogers EA, Gutierrez-Arango S, Israel E, Freed LE, Herr HM. Acquisition of Surface EMG Using Flexible and Low-Profile Electrodes for Lower Extremity Neuroprosthetic Control. IEEE Trans Med Robot Bionics. 2021 Aug;3(3):563-572. doi: 10.1109/TMRB.2021.3098952. PMID: 34738079; PMCID: PMC8562690.

Publication

Design and preliminary results of a reaction force series elastic actuator for bionic knee and ankle prostheses

M. E. Carney, T. Shu, R. Stolyarov, J. F. Duval and H. M. Herr, "Design and Preliminary Results of a Reaction Force Series Elastic Actuator for Bionic Knee and Ankle Prostheses," in IEEE Transactions on Medical Robotics and Bionics, vol. 3, no. 3, pp. 542-553, Aug. 2021, doi: 10.1109/TMRB.2021.3098921.

Publication

Neural Interfacing Architecture Enables Enhanced Motor Control and Residual Limb Functionality Post Amputation

Srinivasan SS, Gutierrez-Arango S, Teng AC, Israel E, Song H, Bailey ZK, Carty MJ, Freed LE, Herr HM. Neural interfacing architecture enables enhanced motor control and residual limb functionality postamputation. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2019555118. doi: 10.1073/pnas.2019555118

Publication

A cutaneous mechanoneural interface for neuroprosthetic feedback

S. Srinivasan, S., M. Herr, H. A cutaneous mechanoneural interface for neuroprosthetic feedback. Nat Biomed Eng (2021). https://doi.org/10.1038/s41551-020-00669-7

Publication

Agonist-antagonist myoneural interface amputation preserves proprioceptive sensorimotor neurophysiology in lower limbs

S. S. Srinivasan, G. Tuckute, J. Zou., Guiterrez S., Seong H., Barry R., Herr H. “Agonist Antagonist Myoneural Interface Amputation Preserves Proprioceptive Sensorimotor Neurophysiology in Lower Limbs”, Science Translational Medicine (2020)

Publication

Flexible Dry Electrodes for EMG Acquisition within Lower Extremity Prosthetic Sockets

Yeon, Seong Ho, et al. "Flexible Dry Electrodes for EMG Acquisition within Lower Extremity Prosthetic Sockets." 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob). IEEE.

Publication

An Ankle-Foot Prosthesis for Rock Climbing Augmentation

E. A. Rogers, M. E. Carney, S. H. Yeon, T. R. Clites, D. Solav and H. M. Herr, "An Ankle-Foot Prosthesis for Rock Climbing Augmentation," in IEEE Transactions on Neural Systems and Rehabilitation Engineering, doi: 10.1109/TNSRE.2020.3033474.

Publication

Electric-Energetic Consequences of Springs in Lower-Extremity Powered Prostheses on Varied Terrain

M. E. Carney and H. Herr, "Electric-Energetic Consequences of Springs in Lower-Extremity Powered Prostheses on Varied Terrain," 2020 8th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob), New York City, NY, USA, 2020, pp. 989-996, doi: 10.1109/BioRob49111.2020.9224458.

Publication

Design and control of a Two-Degree-of-Freedom powered ankle-foot prosthesis

T.-H. Hsieh, “Design and Control of a Two-degree-of-freedom Powered Ankle-Foot Prosthesis”, Master’s thesis, Massachusetts Institute of Technology, 2019.

Publication

Magnetomicrometry: Tissue Length Tracking via Implanted Magnetic Beads

C. Taylor, Magnetomicrometry : Tissue length tracking via implanted magnetic beads (2020). https://dspace.mit.edu/handle/1721.1/130210

Publication

Design and Evaluation of a Reaction-Force Series Elastic Actuator Configurable as Biomimetic Powered Ankle and Knee Prostheses

Carney, Matthew E. “Design and Evaluation of a Reaction-Force Series Elastic Actuator Configurable as Biomimetic Powered Ankle and Knee Prostheses By.” Massachusetts Institute of Technology, 2020.

Publication

Low-latency tracking of multiple permanent magnets

C. R. Taylor, H. G. Abramson, and H. M. Herr, “Low-Latency Tracking of Multiple Permanent Magnets,” IEEE Sensors Journal, pp. 1–11, 2019.

Publication

Coordination of Lower Limb Movement Utilizing the Agonist-Antagonist Myoneural Interface

Publication

Retinal supplementation augments optogenetic stimulation efficacy in vivo

S. Srinivasan, B. Schelhaas, B. E. Maimon, H. Song, H. M. Herr, Retinal supplementation augments optogenetic stimulation efficacy in vivo. J. Neural Eng. (2019)

Publication

A caprine model of the agonist-antagonist myoneural interface as implemented at the above- and below-knee amputation levels.

T. R. Clites, M. J. Carty, S. S. Srinivasan, S. G. Talbot, R. Branemark, H. M. Herr, A caprine model of the agonist-antagonist myoneural interface as implemented at the above- and below-knee amputation levels.: Plastic and Reconstructive Surgery. 2019

Publication

Polyimide Electrode-Based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration

S. Srinivasan, K. Vyas, M. McAvoy, P. Calvaresi, O. Khan, R. Langer, D. Anderson, H. Herr, Polyimide Electrode-based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration. Front. Neurol. 10 (2019),

Publication

Towards functional restoration for persons with limb amputation: A dual-stage implementation of regenerative AMIs

S. S. Srinivasan, M. Diaz, M. Carty, H. M. Herr, Towards functional restoration for persons with limb amputation: A dual-stage implementation of regenerative agonist-antagonist myoneural interfaces. Sci. Rep. 9, 1981 (2019).

Publication

A Framework for Measuring the Time-Varying Shape and Full-Field Deformation of Residual Limbs Using 3-D Digital Image Correlation

Solav, D., Moerman, K. M., Jaeger, A. M., & Herr, H. (2019). A framework for measuring the time-varying shape and full-field deformation of residual limbs using 3D digital image correlation. IEEE Transactions on Biomedical Engineering, 66(10), 2740-2752.

Publication

Closed-loop functional optogenetic stimulation

Shriya S. Srinivasan, Benjamin E. Maimon, Maurizio Diaz, Hyungeun Song and Hugh M. Herr, Nature Communications, volume 9, article number: 5303 (2018)

Publication

Spectrally distinct channelrhodopsins for two-colour optogenetic peripheral nerve stimulation

Publication

Spectrally distinct channelrhodopsins for two-colour optogenetic peripheral nerve stimulation

B. E. Maimon, K. Sparks, S. S. Srinivasan, A. N. Zorzos, H. M. Herr, Spectrally distinct channelrhodopsins for two-colour optogenetic peripheral nerve stimulation. Nature Biomedical Engineering 2, 485–496 (2018).

Publication

MultiDIC: An Open-Source Toolbox for Multi-View 3D Digital Image Correlation

Solav, D., K. M. Moerman, A. M. Jaeger, K. Genovese, and H. M. Herr. MultiDIC: an Open-Source Toolbox for Multi-View 3D Digital Image Correlation. IEEE Access 6:30520–30535, 2018.

Publication

Proprioception from a neurally controlled lower-extremity prosthesis

T. R. Clites, M. J. Carty, J. B. Ullauri, M. E. Carney, L. M. Mooney, J.-F. Duval, S. S. Srinivasan, H. M. Herr, Proprioception from a neurally controlled lower-extremity prosthesis. Sci. Transl. Med. 10, eaap8373 (2018).

Publication

Development and Evaluation of a Powered Artificial Gastrocnemius for Transtibial Amputee Gait

M. Eilenberg, J. Kuan, and H. Herr. Development and Evaluation of a Powered Artificial Gastrocnemius for Transtibial Amputee Gait, Journal of Robotics, vol. 2018, Article ID 5951965, 15 pages, 2018.

Publication

Translational Motion Tracking of Leg Joints for Enhanced Prediction of Walking Tasks

Stolyarov, R. M., Burnett, G., & Herr, H. (2017). Translational Motion Tracking of Leg Joints for Enhanced Prediction of Walking Tasks. IEEE Transactions on Biomedical Engineering, 1-1. doi:10.1109/tbme.2017.2718528

Publication

On prosthetic control: A regenerative agonist-antagonist myoneural interface

S. S. Srinivasan, M. J. Carty, P. W. Calvaresi, T. R. Clites, B. E. Maimon, C. R. Taylor, A. N. Zorzos, H. Herr, On prosthetic control : A regenerative agonist-antagonist myoneural interface, 2, eaan2971 (2017).

Publication

A Caprine Model of a Novel Amputation Paradigm for Bi-directional Neural Control of a Bionic Limb

T. R. Clites, M. J. Carty, H. M. Herr, in Plastic Surgery Research Council, (2017), p. 119.

Publication

A murine model of a novel surgical architecture for proprioceptive muscle feedback

T. R. Clites, M. J. Carty, S. Srinivasan, A. N. Zorzos, H. M. Herr, A murine model of a novel surgical architecture for proprioceptive muscle feedback and its potential application to control of advanced limb prostheses., J. Neural Eng. 14, aa614b (2017).

Publication

A murine model of a novel surgical architecture for proprioceptive muscle feedback and its potential application to control of advanced limb

Clites TR, Carty MJ, Srinivasan S, Zorzos AN, Herr HM. J Neural Eng. 2017 EPub Feb 17;14(3):036002.

Publication

Transdermal optogenetic peripheral nerve stimulation

Maimon BE, Zorzos AN, Bendell R, Harding A, Fahmi M, Srinivasan S, Calvaresi P, Herr HM. J Neural Eng. 2017 Feb 3;14(3): 034002

Publication

Low-Cost Methodology for Skin Strain Measurement of a Flexed Biological Limb.

Lin, B., Moerman, K. M., McMahan, C. G., Pasch, K. A., & Herr, H. M. Low-Cost Methodology for Skin Strain Measurement of a Flexed Biological Limb. IEEE Transactions on Biomedical Engineering, PP(99), 2016.

Publication

FlexSEA: Flexible Scalable Electronics Architecture for Wearable Robotic Applications

J.F. Duval, H. M. Herr

Publication

FlexSEA-Execute: Advanced Motion Controller for Wearable Robotic Applications

J.F. Duval, H. M. Herr

Publication

Human Leg Model Predicts Muscle Forces, States, and Energetics during Walking

J. Markowitz and H. Herr. Human Leg Model Predicts Muscle Forces, States, and Energetics during Walking, PLoS Computational Biology, vol. 5, no. 12, May. 2016.

Publication

Assessment of Nerve Regeneration through a Novel Microchannel Array

B. Maimon, A. N. Zorzos, K. W. Song, R. Bendell, R. Riso, H. M. Herr

Publication

Multi-Material 3-D Viscoelastic Model of a Transtibial Residuum from In-vivo Indentation and MRI Data

Sengeh DM, Moerman, K. M., Petron A, Herr H.M.

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Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology

H. M. Herr, T. R. Clites, B. Maimon, A. Zorzos, M. J. Carty, J.-F. Duval, Method And System For Providing Proprioceptive Feedback And Functionality Mitigating Limb Pathology. US Pending Patent 62/276422 (2016).

Publication

Biomechanical walking mechanisms underlying the metabolic reduction caused by an autonomous exoskeleton

L. M. Mooney, H. M. Herr

Publication

Peripheral Neural Interface Via Nerve Regeneration to Distal Tissues

H. M. Herr, R. R. Riso, K. W. Song, R. J.Casler, M. J. Carty, Peripheral Neural Interface Via Nerve Regeneration to Distal Tissues. US Patent US20160346099 (2016).

Publication

Control of tension-compression asymmetry in Ogden hyperelasticity with application to soft tissue modelling

Moerman, K. M., Simms, C. K., Nagel, T. Control of tension-compression asymmetry in Ogden hyperelasticity with application to soft tissue modelling Journal of the Mechanical Behavior of Biomedical Materials, 56, 218–228, 2016

Publication

“Motion compensation in a tomographic ultrasound imaging system: toward volumetric scans of a limb for prosthetic socket design”

B.J. Ranger, M. Feigin, N. Pestrov, X. Zhang, V. Lempitsky, H.M. Herr, B.W. Anthony. “Motion compensation in a tomographic ultrasound imaging system: toward volumetric scans of a limb for prosthetic socket design”. Proceedings of the IEEE Engineering in Medicine and Biology Conference, 2015.

Publication

Design and testing of a bionic dance prosthesis

E. J. Rouse, N. C. Villagaray-Carski, R. W. Emerson, H. M. Herr

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FlexSEA: flexible, scalable electronics architecture for wearable robotic applications

Duval, JF "FlexSEA: flexible, scalable electronics architecture for wearable robotic applications"

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Autonomous exoskeleton reduces metabolic cost of human walking

L. M. Mooney, E. J. Rouse and H. M. Herr. Autonomous exoskeleton reduces metabolic cost of human walking, Journal of NeuroEngineering and Rehabilitation, vol. 11, pp. 151, November. 2014

Publication

Autonomous exoskeleton reduces metabolic cost of human walking during load carriage

L. M. Mooney, E. J. Rouse, H. M. Herr

Publication

Clutchable series-elastic actuator: Implications for prosthetic knee design

E. J. Rouse, L. M. Mooney and H. M. Herr Clutchable series-elastic actuator: Implications for prosthetic knee design International Journal of Robotics Research, 2014, in press

Publication

Design of a Clutch–Spring Knee Exoskeleton for Running

G. Elliott, A. Marecki and H. Herr. Design of a Clutch–Spring Knee Exoskeleton for Running, Journal of Medical Devices, vol 8, no. 3, 031002-031002-11, July. 2014.

Publication

Voxel-based Fabrication through Material Property Mapping

E.L. Doubrovski, Elizabeth Tsai, D. Dikovsky, J.M.P. Geraedts, Hugh Herr, Neri Oxman

Publication

Autonomous exoskeleton reduces metabolic cost of walking

L. M. Mooney, E. J. Rouse and H. M. Herr. Autonomous exoskeleton reduces metabolic cost of walking, International Conference of the IEEE Engineering in Medicine and Biology Society, August. 2014.

Publication

A variable impedance prosthetic socket for a transtibial amputee designed from MRI data

D. Sengeh, H. M. Herr

Publication

A clutchable series-elastic actuator: design of a robotic knee prosthesis for minimum energy consumption

E. J. Rouse, L. M. Mooney, E. C. Martinez-Villalpando and H. M. Herr A clutchable series-elastic actuator: design of a robotic knee prosthesis for minimum energy consumption, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013

Publication

Continuously-Variable Series-Elastic Actuator

L. M. Mooney and H. M. Herr Continuously-Variable Series-Elastic Actuator, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013

Publication

Proportional EMG Control of Ankle Plantar Flexion in a Powered Transtibial Prosthesis

J. Wang, O. A. Kannape, and H. M. Herr Proportional EMG Control of Ankle Plantar Flexion in a Powered Transtibial Prosthesis, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013

Publication

Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series

D. Hill and H. M. Herr. Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series, Proceedings of the IEEE International Conference on Rehabilitation Robotics, 2013.