Project

Synthetic Genome Engineering

Groups

We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifying and engineering endonucleases from diverse living systems, along with targeting with synthetic molecules. Together these components confer greater stability, minimize off-target DNA cleavage, and eliminate sequence restrictions for precision genetic manipulations within cells.

We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifying and engineering endonucleases from diverse living systems, along with targeting with synthetic molecules. Together these components confer greater stability, minimize off-target DNA cleavage, and eliminate sequence restrictions for precision genetic manipulations within cells.