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Rui Qing, Qiuyi Han, Michael Skuhersky, Haeyoon Chung, Myriam Badr, View ORCID ProfileThomas Schubert, and Shuguang Zhang. PNAS first published November 27, 2019 (https://doi.org/10.1073/pnas.1909026116). Edited by Alan R. Fersht, University of Cambridge, Cambridge, United Kingdom, and approved October 30, 2019 (received for review May 24, 2019).