Project

Research Area | Rapid Fabrication and Deployment of Medical Devices and Technologies

Pratik Shah

We have significant expertise and motivation to bring problems from the clinic and society into the laboratory to develop novel bioengineering solutions and perform real world prospective clinical evaluations. We have supported patients and physicians by providing innovative medical technologies using mobile phones, sensors and digital wearable devices for generating at home and point-of-care real world data and evidence. For example, in a study published in the British Medical Journal we evaluated the significance and efficacy of real world data generated from the United States Food and Drug Administration approved advanced technology-enabled, non-invasive diagnostic screening (TES) smartphones and other point-of-care medical imaging devices vs. conventional vital signs examinations (Project link). This study led to significant insights regarding strategies for developing TES technologies at MIT that are ready for deployment and designed for effective and scalable primary care and real world evidence generation. Examples: 

  • In collaboration with MIT Chemical Engineering and other researchers we have devel… View full description

We have significant expertise and motivation to bring problems from the clinic and society into the laboratory to develop novel bioengineering solutions and perform real world prospective clinical evaluations. We have supported patients and physicians by providing innovative medical technologies using mobile phones, sensors and digital wearable devices for generating at home and point-of-care real world data and evidence. For example, in a study published in the British Medical Journal we evaluated the significance and efficacy of real world data generated from the United States Food and Drug Administration approved advanced technology-enabled, non-invasive diagnostic screening (TES) smartphones and other point-of-care medical imaging devices vs. conventional vital signs examinations (Project link). This study led to significant insights regarding strategies for developing TES technologies at MIT that are ready for deployment and designed for effective and scalable primary care and real world evidence generation. Examples: 

  • In collaboration with MIT Chemical Engineering and other researchers we have developed and published protocols for a POC lateral flow diagnostic strip and bio-digital wearable devices to detect biomarkers in human saliva samples. Biomarkers such as matrix metalloproteinases-8 and -9, pH and nitric oxide linked to oral diseases, stress and human physiology have been successfully integrated with our platforms (Project link). 
  • A study of a low-cost mask to screen for sleep apnea through physiological monitoring: respiratory activity (airflow and nasal air pressure) and sleep behavior (motion and noise) has been published (Project link).
  • Construction and validation of low-cost, point-of-care, near-infrared imaging devices to diagnose dental caries, cracks, and demineralization without the use of ionizing X-rays have been published (Project link, Project link, Project link).
  • We have open-sourced the construction and the algorithm of porphyrin imaging devices and also created a cell phone clip that can be used on a mobile phone camera (Project link).