Designer partial water-soluble GPCR CXCR4QTY29 variant receptor retains ligand binding activity and in vivo cell singling.
Unexpected findings in chemokine receptors once believed to be non-functional open up new fields of scientific inquiry.
Team designs antibody-like receptor proteins that can bind to cytokines, as possible strategy for treating coronavirus and other infections.
The award recognizes a recent, highly significant contribution to the application of chemistry in the study of proteins.