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Molecular Machines group
The research described here has been published on a preprint server but has not yet been peer-reviewed by scientific or medical experts.T...
Programmable CRISPR enzymes are powerful and versatile tools for genome editing. They, however, require a specific protospacer adjacent m...
In April 2019, Shuguang Zhang's lab started to use the QTY code to design a class of water-soluble cytokine receptors, including interfer...
In collaboration with Prof. Tao Fei’s lab (Shanghai Jiaotong University, China)In addition to a large number of membrane proteins that co...
Structure and function studies of membrane proteins, particularly G protein-coupled receptors (GPCRs) and multipass transmembrane protein...
In collaboration with Prof. Horst Vogel and Dr. Horst Pick (EPFL, Lausanne, Switzerland).G protein-coupled receptors (GPCRs) are vital fo...
In collaboration with Prof. Uwe Sleytr and Dr. Andreas Breitwieser (BOKU, Vienna, Austria).Bioelectronics is an emerging antidisciplinary...
There are 20 chemokine receptors that bind their respective chemokines. It is not currently understood how these structurally similar rec...
Protein-protein interactions (PPIs) are an essential part of many biological pathways in living organisms. With use cases such as regulat...
The CRISPR-Cas9 system has proven to be a versatile tool for genome editing, with numerous implications in medicine, agriculture, bi...
Affinity is a high-level machine learning API (Application Programming Interface) dedicated exclusively to molecular geometry. Affinity i...
We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifyi...
Technological advances in the past decade have allowed us to take a close look at the proteomes of living organisms. As a result, more th...