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Project

CAREER: Wirelesss Sensing for In Vivo Medical Devices

This NSF-funded project develops wireless networking systems for deep-tissue micro-implants. The micro-implants may be swallowed or injected into the human body and used for applications such as delivering drugs or monitoring internal human vitals. The challenge in building these systems arises from the power, size, and longevity constraints of micro-implants as well as the anatomical complexity of the human body and its interaction with wireless signals. By overcoming these challenges, this research will enable a new generation of networked micro-implants that can actively contribute to human health and well-being.

The goal of this project is to design and build practical wireless systems that are capable of communicating with and localizing micro-implants at near-zero power. To this end, the researchers plan to augment micro-implants with backscatter sensors and develop algorithms, protocols, and system architectures for these sensors. The proposed research contributions encompass developing (i) algorithms for reliable and adaptive deep-tissue communication, (ii) techniques for accurate cross-medium backscatter localization, and (iii) integrated sensing platforms that combine communication, localization, and sensing on battery-free micro-implants. The proposed research will extend beyond the conception of algorithms and systems to the implementation and evaluation of real-world prototypes. The designs will be integrated on micro-implants with sensing and actuation capabilities, and will be evaluated in a number of applications such as wireless smart pills for targeted drug delivery and internal vital sign sensors for continuous in-vivo monitoring.

This project is funded by NSF Award 1844280. Below is a list of publications that resulted from this project and their associated pages.

Projects

Patents

Granted patents (2):

Unsoo Ha, Junshan Leng, Alaa Khaddaj, Yunfei Ma, Tzu Ming Hsu, Zexuan Zhong, Fadel Adib, “Methods and Apparatus for Radio Frequency Sensing in Diverse Environments,” US Patent No. 10,872,209 B2, December 22, 2020.

Unsoo Ha, Junshan Leng, Alaa Khaddaj, Yunfei Ma, Tzu Ming Hsu, Zexuan Zhong, Fadel Adib, “Methods and Apparatus for Radio Frequency Sensing in Diverse Environments,” US Patent No. 11,309,291 B2, April 19, 2022.

Pending patents (6):

Fadel Adib, Laura Noelle Dodds, Aline Eid, Isaac S. Perper, “A Handheld Fine-Grained RFID Localization System with Complex-Controlled Polarization,” US Patent Application 18/505,355, filed November 8, 2023.

Fadel Adib, Tara Boroushaki, Maisy Lam, Laura Dodds, Aline Eid, “Augmented Reality with Non-Line-of-Sight Perception,” US Patent Application 18/355,600, filed July 20, 2023.

Tara Boroushaki, Isaac Perper, Fadel Adib, “Robotic Grasping via RF-Visual Sensing and Learning,” PCT Patent Application No. 17/819,685, filed August 15, 2022.

Tara Boroushaki, Junshan Leng, Fadel Adib, “System and method for location determination and robot control,” US Patent Application No. 17/530,603, filed November 19, 2021.

Unsoo Ha, Sohrab Madani, Fadel Adib, “Contactless Stress Monitoring Using Wireless Signals,” US Patent Application No. 63/276,889, filed November 8, 2021.

Unsoo Ha, Fadel Adib, “Contactless Seismography,” PCT Patent Application No. 63/075,432, filed August 27, 2021

Publications