Research
Space Exploration Initiative

Space Exploration Initiative
Research
Synthetic Neurobiology

Revealing insights into the human condition and repairing brain disorders via novel tools for mapping and fixing brain computations
Research
Molecular Machines

Engineering at the limits of complexity with molecular-scale parts
Research
Open Ocean

Open Ocean
Project Research

Brainstorm: Anima Mundi

We'd like to introduce you to a very special neuroscience project that we are currently conducting in the setting of a traditional fine a...
Research
Center for Extreme Bionics

Center for Extreme Bionics
Archived
Research
Design Fiction

Sparking discussion about the social, cultural, and ethical implications of emerging technologies through design and storytelling
Project Research

Ocean Cultures

Māori residents on the Cook Islands have a long and deep connection to their island and ocean ecosystem.  The Māori concept of Raui ...
Project Research

Search for Extra-Terrestrial Genomes (SETG)

The widespread synthesis of common organic building blocks in space could have biased life beyond Earth towards chemical similarities to ...
Publication Research

Chimeric CRISPR guides enhance Cas9 target specificity

Noah Jakimo, Pranam Chatterjee, Joseph M. Jacobson. Chimeric CRISPR guides enhance Cas9 target specificity, doi: https://doi.org/10.1101/147686
Project Research

Preventing Tick-Borne Disease by Permanently Immunizing Mice

Lyme disease is the most common vector-borne infection in North America. People are infected when bitten by ticks; ticks are typically in...
Archived
Project Research

Brain-Controlled Interface for the Motile Control of Spermatozoa

The reproductive organs of the female body have long been a site of contention, where opposing ideologies in religion, politics, and cult...
Archived
Project Research

Daisy Drives

Who should decide whether, when, and how to alter the environment? It's a hard question, especially when the decision will impact people ...
Project Research

Synthetic Genome Engineering

We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifyi...
Research
Sculpting Evolution

Exploring evolutionary and ecological engineering
Project Research

Responsive Science

Responsive Science is a way of conducting research that invites openness and community involvement from the earliest stages of each proje...
Article Research

Voters to decide on intro of altered mice to combat Lyme

Residents are invited to weigh in on a plan to release genetically-modified mice on Nantucket to combat tick-borne diseases
Article Research

Lyme disease is spreading, and it’s partly this mouse’s fault

Black-legged ticks in forests of the Northeast and Midwest have a variety of options for the three blood meals they consume in their life...
Post Research

Daisy drive: a local, open, and community-responsive approach to solving ecological problems

Pursue modular "daisy drive" platforms with the potential to safely, efficiently, and reversibly edit local sub-populations of organisms
Article Research

Transparency advocate shakes up genetic engineering

Kevin Esvelt has emerged as a leader in the debate about the ethics and politics of releasing genetically engineered animals.
Project Research

Gene Editing and Biomedical Ethics

The initiative, working with George Church, professor of genetics at Harvard Medical School, and Kevin Esvelt, head of the Sculpting Evol...
Article Research

This Woman Just Figured Out How to Control Sperm with Her Brain

Transdisciplinary artist Ani Liu spoke to us about her project as commentary on the state of reproductive rights today.
Article Research

Cracking the Genetic Code with Kevin Esvelt

Kevin Esvelt leads the Sculpting Evolution Group at MIT. Their work explores “evolutionary and ecological engineering and responsive science
Project Research

Egstrogen Farms

A transgenic chicken commercial for ovulating womenEsgtrogen Farms is a fictional company that raises genetically modified chickens that ...
Project Research

Tranceflora—Amy's Glowing Silk

We collaborated with NIAS (National Institute of Agricultural Science) to genetically engineer silkworms to develop new kinds of silk for...
Article Research

How CRISPR gene editing puts scientists in the driver’s seat of evolution

Imagine you could edit a mouse’s genes to be resistant to Lyme Disease. The mouse would breed and evolution would take its course, leadin...
Project Research

Studying the Evolution of Gene Drive Systems

How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drive...