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Project Research

RiboGen: RNA Sequence and Structure Co-Generation

RNA is a fundamental biomolecule that stands at the intersection of modern biology and the origins of life. It carries genetic instruc…
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Space Enabled

Advancing justice in Earth's complex systems using designs enabled by space
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Sculpting Evolution

Cultivating wisdom through evolutionary and ecological engineering
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Affective Computing

Advancing human wellbeing by developing new ways to communicate, understand, and respond to emotion
Project Research

Microgravity Research Flights with the Space Exploration Intiative

The Space Exploration Initiative charters an annual ZERO-G parabolic flight for 10-15 projects and 25 researchers across MIT Media Lab, sev…
Project Research

Measuring AI performance in biology
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Project Research

Air sampling for virus detection

Examining the role of air sampling in pathogen biosurveillance. 
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Publication Research

LLMs Outperform Experts on Challenging Biology Benchmarks

Justen, L. (2025). Llms outperform experts on challenging biology benchmarks (No. arXiv:2505.06108). arXiv. https://doi.org/10.48550/arXiv.2505.06108
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Conformable Decoders

Converting the patterns of nature and the human body into beneficial signals and energy
Article Research

A brief history of expansion microscopy

Since its 2015 debut by an MIT team, expansion microscopy has advanced research on kidneys, seeds, Alzheimer’s, viruses, and more.
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Nano-Cybernetic Biotrek

Inventing disruptive technologies for nanoelectronic devices and creating new paradigms for life-machine symbiosis
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Tangible Media

Invent new tangible and embodied interactions that inspire and engage people
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Biomechatronics

Enhancing human physical capability
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Responsive Environments

Augmenting and mediating human experience, interaction, and perception with sensor networks
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Opera of the Future

Extending expression, learning, and health through innovations in musical composition, performance, and participation
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Molecular Machines

Engineering at the limits of complexity with molecular-scale parts
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Camera Culture

Making the invisible visible–inside our bodies, around us, and beyond–for health, work, and connection
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Media Lab Research Theme: Life with AI

Life with AI | Designing the future of smart systems to improve the human experience
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Media Lab Research Theme: Future Worlds

Future Worlds | Design and action for the future we want to live in
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Media Lab Research Theme: Decentralized Society

Decentralized Society | Architecting the new internet for the good of the people
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Media Lab Research Theme: Cultivating Creativity

Cultivating Creativity | Catalyzing a global movement enabling everyone to unlock and unleash their individual and collective creativity
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Media Lab Research Theme: Connected Mind + Body

Connected Mind + Body | Revolutionizing the future of mental and physical wellbeing
Project Research

The Gravity Loading Countermeasure Skinsuit

By Rachel BellisleOverview:The Gravity Loading Countermeasure Skinsuit (GLCS or “Skinsuit”) is an intravehicular activity suit for astronau…
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Fluid Expressions - Art and Craft in Microgravity

When imagining human life in space, how will we express our humanity and creativity in an alien environment? Can the art we make both refle…
Project Research

Evolving Decoy ACE2 Receptor Mimics As COVID-19 Therapeutics

COVID-19 has over only a few short months resulted in the deaths of >400,000 people worldwide (as of mid-June 2020) and has forced many …
Project Research

Nanoscale mapping of bio-molecular building blocks of brain

For more details and recent updates visit:  https://web.mit.edu/deblina-sarkar/For understanding the brain structure, it is neces…
Project Research

conformable Ultrasound Patch (cUSP) For Cavitation-Enhanced Transdermal Drug Delivery

Ultrasound-induced transdermal drug delivery (sonophoresis) has long lingered in the by-lanes of academic and industrial research, and has …
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Space Exploration Initiative

Designing, prototyping, and building the artifacts of our sci-fi space future
Project Research

Life-Nanomachine Synergism

For details and recent updates visit:  https://web.mit.edu/deblina-sarkar/Nanoelectronics has the potential to enable radical too…
Article Research

It shouldn’t be easy to buy synthetic DNA fragments to recreate the 1918 flu virus

In STAT, Media Lab Professor Kevin Esvelt calls for stronger regulation of synthetic DNA.
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Community Biotechnology

Empowering communities through the life sciences + biotechnology
Article Research

Uruguay wants to use gene drives to eradicate devastating screwworms

The project was inspired by a conversation with Media Lab Professor Kevin Esvelt, a pioneer in developing gene drives.
Article Research

Life in space: Preparing for an increasingly tangible reality

The Space Exploration Initiative supports research across and beyond MIT in two microgravity flights this spring.
Project Research

QTY code designs for water-soluble beta-barrel transmembrane proteins

In addition to a large number of membrane proteins that comprise most alpha-helix transmembrane segments, there are also many transmembrane…
Article Research

Protein study could help researchers develop new antibiotics

Researchers created a water-soluble version of an important bacterial enzyme, which can be used in drug screens to identify new antibiotics.
Project Research

Studying the evolution of gene drive systems

How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drives?…
Article Research

CRISPR gene drives and the future of evolution

Professor Kevin Esvelt talks to science journalist Hannah Thomasy about the power—and the risks—of biotechnology.
Publication Research

Electronic Textile Sensors for Decoding Vital Body Signals: State-of-the-Art Review on Characterizations and Recommendations

Shuvo, I. I., Shah, A., Dagdeviren, C.†, “Electronic Textile Sensors for Decoding Vital Body Signals: State-of-the-art Review on Characterizations and Recommendations”, https://doi.org/10.1002/aisy.202100223, Advanced Intelligent Systems, 4, 2100223, 2022.
Project Research

conformable Facial Code Extrapolation Sensor (cFaCES)

AbstractDevices that facilitate nonverbal communication typically require high computational loads or have rigid and bulky form factors&nbs…
Project Research

Bio-Digital Wearables for Space Health Enhancement

Living in space could have significant physical and mental impacts on astronauts. Wearables have the potential to play a critical role in m…
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Research
Mediated Matter

Designing for, with, and by nature
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Candlewax Rockets: A Green Alternative for In-Space Propulsion

The Space Enabled Research Group is exploring the potential of using beeswax and candle wax as potential fuels for satellites in space. Bee…
Project Research

conformable Multimodal Sensory Facemask (cMaSK)

Facemasks are used to reduce exposure to viruses and other environmental hazards such as air pollution, and integrating wearable electronic…
Project Research

How to Grow (Almost) Anything - A New Model for Global Synthetic Biology Education

A Distance Learning Model for Global Laboratory-Based Synthetic Biology Education Synthetic Biology ( SynBio) tools hold the…
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Project Research

Aguahoja

Programmable Water-Based Biocomposites for Digital Design and Fabrication across ScalesAguahoja is an exploration of nature’s design space.…
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Project Research

Aguahoja II

Aguahoja II builds upon the platform technology of its predecessor, enabling large-scale multi-material 3D printing with abundant, organic …
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Project Research

CyberBiome

CyberBiome is a programmable bio-digital organ, a wearable biosynthesis platform for personalized, on-demand production of therapeutics and…
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Peristaltic Suit

​Prolonged exposure to microgravity is known to cause various acute health risks, including muscle atrophy, bone loss, cardiovascular decon…
Article Research

Patches to the rescue

MIT Technology Review reports on transdermal drug delivery research from the Conformable Decoders group, led by Professor Canan Dagdeviren.
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Targeted intracellular degradation of SARS-CoV-2 via computationally optimized peptide fusions

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has elicited a global health crisis of catastrophic proportions. With on…
Project Research

Secure DNA

A world in which thousands of people can construct and release autonomous biological agents is unlikely to flourishProfessor Kevin Esvelt, …
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A tailored, electronic textile conformable suit for large-scale spatiotemporal physiological sensing in vivo

The rapid advancement of electronic devices and fabrication technologies has further promoted the field of wearables and smart textiles. Ho…
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Understanding Molecular Evolution

Humanity has harnessed evolution to sculpt domesticated animals, crops, and molecules, but the process remains a black box. Which combinati…
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Mice Against Ticks - Preventing tick-borne disease by permanently immunizing mice

Lyme disease is the most common vector-borne infection in North America. People are infected when bitten by ticks; ticks are typically infe…
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Project Research

Aguahoja III

Aguahoja III expands the capabilities of a broad library of sustainable, organic 3D materials with generative patterns that countervail str…
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Envirome Monitoring with CRISPR Biosensors

In recent years, there has been an increase in low-cost and open-source electronic and chemical sensors that hobbyists, concerned citizens,…
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Radiofungi: Biological Pigments for Radioprotection

A major concern for manned missions is space radiation. Ionizing radiation is known to pose both acute and chronic risks to many organisms,…
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Project Research

H0TP0T

By Larissa Zhou and Adam ZacharFood is crucial to maintaining the physical and psychological health of humans in space. Eating food pr…
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Project Research

Reconfigurable space structures

Rapid prototyping platforms such as 3D printers used for digital fabrication are today able to manufacture custom objects for specific task…
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Project Research

Zenolith - An Interplanetary Time Device

On Earth, morning, noon, and night have their own specific meanings. The feeling of a second or a minute passing by, the shortening of the …
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Project Research

Self Assembling Space Frames

Ever wish you could toss your folded up tent and have it self-assemble mid-air?  Well...you can. In a zero gravity environment.Self As…
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Project Research

Harmony in Precarity

By Po-Hao ChiHow could microgravity/hypergravity shape our perceptual experience of listening with weightlessness? How can we seek to explo…
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Miniature Optical Steered Antenna for Intersatellite Communication (MOSAIC)

The Miniature Optical Steered Antenna for Intersatellite Communications (MOSAIC)By Shreeyam KackerThe Miniature Optical Steered Antenn…
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Project Research

Moving Liquids With No Moving Parts

Solid-state microfrabricated devices are in development to replace contemporary heavy mechanical components for use in spacecraft propellan…
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Ø-scillation: oscillating chemistry in zero gravity and beyond

How did life originate? Nobody knows. Life might not even be native to our Earth - it might have come from asteroids or the interstellar me…
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AgriFuge

By Somayajulu Dhulipala and Manwei ChanAs humanity explores deeper into space, long-duration missions will require horticulture activities …
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Panspermia

By Nancy Valladares and Rae Yuping HsuThis project is an art performance that seeks to rethink imaginaries of multispecies surviv…
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SpaceHuman 2.0

SpaceHuman is a soft robotics device designed to facilitate the exploration of environments with reduced gravity in a view of democratizati…
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ELI: Electronic Life-detection Instrument

Life on Mars, if it exists, could have been transferred between Earth and Mars due to meteorite impacts. The Search for Extra-Terrestrial G…
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Project Research

The Telemetron

Today, the environments that humans occupy in space are designed for survival. Humans are carefully shuttled to and from space, and during …
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Receptor S-layer Electrical Nano Sensing Array (RESENSA)

A modular, membrane protein design based biomimetic sensing system named RESENSA (Receptor S-layer Electrical Nano Sens…