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Revealing insights into the human condition and repairing brain disorders via novel tools for mapping and fixing brain computations
Lower-extremity amputation surgery has not seen significant change since the Civil War. This research is focused on the development of no...
The reproductive organs of the female body have long been a site of contention, where opposing ideologies in religion, politics, and cult...
Space Exploration Initiative
Kevin Esvelt leads the Sculpting Evolution Group at MIT. Their work explores “evolutionary and ecological engineering and responsive science
How Canan Dagdeviren is going about setting up a new research group at the Media Lab.
10.1109/JTEHM.2017.2695194
Designing for, with, and by nature
Brain circuits are large, 3D structures. However, the building blocks—proteins, signaling complexes, synapses—are or...
The gram-positive cocci Streptococcus pneumoniae causes pneumonia, otitis media, meningitis, and bacteremia in pediatric, elderly, and im...
We collaborated with NIAS (National Institute of Agricultural Science) to genetically engineer silkworms to develop new kinds of silk for...
Making the invisible visible–inside our bodies, around us, and beyond–for health, work, and connection
"Without urgent, coordinated action by many stakeholders, the world is headed for a post-antibiotic era, in which common infections and m...
The Synthetic Apiary proposes a new kind of environment, bridging urban and organismic scales by exploring one of the most important orga...
Creating scalable technologies that evolve with user inventiveness
Enhancing human physical capability
Nearly all classes of wearable and implantable biomedical devices depend on battery power for continuous operation. However, the life spa...
Recent advancements in orthopedic implants have made way for a new generation of bionic limbs that attach directly to the skeleton. Lever...
Exploring evolutionary and ecological engineering
Today’s health sensors (which monitor breathing, heartbeats, steps, etc.) require their users to wear them on their bodies. In contrast, ...
In the United States, there are an estimated 1.7 million people living with amputation, with that number expected to double by 2050. Comp...
Engineering at the limits of complexity with molecular-scale parts
CE 2.0
How we can understand human behavior (rationality, semi-rationality, bounded rationality, and just plain irrationality) in day-to-day behaviors, and in particular in electronic environments.
How to engineer and disseminate powerful, low-cost design and fabrication technologies at a grassroots level.
How to redefine and expand the conceptual framework and language of learning by creating new technologies and spheres of practice.
How radical new collaborations will catalyze a revolution in health.
How to bring the programmability of the digital world to the physical world.
How to build intelligent music systems out of interacting audio-processing agents.
How to distill meaning from complex everyday experiences. Walter Bender is currently on leave.
How to detect the activity of biological molecules with micro- and nanofabricated devices.
How we can construct information technology and intelligence from the fundamental building blocks of physical media: atoms and molecules.
We are providing our tools to the community, and also using them within our lab, to analyze how specific brain mechanisms (molecular, cel...
The brain is a three-dimensional, densely-wired circuit that computes via large sets of widely distributed neurons i...
We have pioneered the development of fully genetically encoded reagents that, when targeted to specific cells, enabl...
Recent advances in artificial limbs have resulted in the provision of powered ankle and knee function for lower extremity amputees and po...
We have developed a set of "optogenetic" reagents: fully genetically encoded reagents that, when targeted to specifi...
Our goals include novel gene logic and data logging systems, as well as DNA scaffolds that can be produced on commercial scales. State of...
New technologies for recording neural activity, controlling neural activity, or building brain circuits, may be capable some day of servi...
How will gene drive systems evolve once released into the wild? Can they be reliably overwritten and blocked by immunizing reversal drive...
We are currently developing novel DNA editing technologies to broaden the scope of genome engineering. Our strategy is based on identifyi...