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Technical summary: Future of clinical development is on the verge of a major transformation due to convergence of large new digital data ...
Staining of tissues sections using chemical and biological dyes has been used for over a century for visualizing various tissue types and...
This study reports an end-to-end deep learning framework for virtual H&E staining, automatic classification, and localization of pros...
Looking beyond smart cities
Virtual and augmented reality headsets are unique as they have access to our facial area, an area that presents an excellent opportunity ...
Virtual Beyond the Cradle
AbstractDevices that facilitate nonverbal communication typically require high computational loads or have rigid and bulky form factors&n...
The rapid advancement of electronic devices and fabrication technologies has further promoted the field of wearables and smart textiles. ...
Health 0.0
Converting the patterns of nature and the human body into beneficial signals and energy
Space Exploration Initiative
Designing systems for cognitive enhancement
Inventing disruptive technologies for nanoelectronic devices and creating new paradigms for life-machine symbiosis
Gelain, F., Luo, Z., Rioult, M. et al. Self-assembling peptide scaffolds in the clinic. npj Regen Med 6, 9 (2021). https://doi.org/10.1038/s41536-020-00116-w
Enhancing human physical capability
The human ankle provides a significant amount of net positive work during the stance period of walking, especially at moderate to fast wa...
Interpreting human electroencephalogram (EEG) is a challenging task and requires years of medical training. We present a framework for le...
Academic research groups, especially the ones directed by new junior faculty, are under pressure to produce high-quality work timely whil...
Two-dimensional radiographs are commonly used for evaluating sub-surface hard structures of teeth, but they have low sensitivity for earl...
Technical summaryUnstructured learning problems without well-defined rewards are unsuitable for current reinforcement learning (RL) appro...
Building intelligent personified technologies that collaborate with people to help them learn, thrive, and flourish.
It was believed that functionalities of G protein-coupled receptors (GPCRs) require full-length sequences which are negated by residue de...
An unexpected discovery of truncated GPCR receptors raises questions about pseudogenes, the "Dark Matter" in genomes and for new devices.
K. Angelino, D. A. Edlund, P. Shah. Near-Infrared Imaging for Detecting Caries and Structural Deformities in Teeth. Journal of Translational Engineering in Health and Medicine (2017). PMID: 28507826
Paper diagnostics can be used for affordable and scalable biomarker detection. We propose new methods for stabilizing cellulose-based imm...
Community Biotechnology
Doze is an IoT enabled platform for personalized scent diffusion and on-skin drug delivery. Leveraging a hydrogel technology, the Doze sy...
Making the invisible visible–inside our bodies, around us, and beyond–for health, work, and connection
Recent advances in medications for neurodegenerative disorders are expanding opportunities for improving the debilitating symptoms suffer...
Improvements in ingestible electronics with the capacity to sense physiological and pathophysiological states have transformed the standa...
Humans can accurately sense the position, speed, and torque of their limbs, even with their eyes shut. This sense, known as proprioceptio...
Hao, SL., Jin D., Zhang, S. & Qing, R. (2020) QTY code-designed water-soluble Fc-fusion cytokine receptors bind to their respective ligands. QRB Discovery 1 (e4) 1-9, Cambridge University Press
Sparking discussion about the social, cultural, and ethical implications of emerging technologies through design and storytelling
Augmenting and mediating human experience, interaction, and perception with sensor networks
Designing for, with, and by nature
Revealing insights into the human condition and repairing brain disorders via novel tools for mapping and fixing brain computations
We have pioneered the development of fully genetically encoded reagents that, when targeted to specific cells, enable their physiology to...
The brain is a three-dimensional, densely-wired circuit that computes via large sets of widely distributed neurons interacting at fast ti...
New technologies for recording neural activity, controlling neural activity, or building brain circuits, may be capable someday of servin...
Complex biological systems such as brain circuits are extended 3-D structures made out of nanoscale building blocks such as proteins, RNA...
We are providing our tools to the community, and also using them within our lab, to analyze how specific brain mechanisms (molecular, cel...
Changing storytelling, communication, and everyday life through sensing, understanding, and new interface technologies
Cultivating wisdom through evolutionary and ecological engineering
Engineering at the limits of complexity with molecular-scale parts
Living Bits : Opportunities and Challenges for Integrating Living Microorganisms in Human-Computer InteractionThere are trillions of livi...
The design of next-generation bionic ankles and knees aims to improve bionic actuators on all metrics: range of motion, power density, ba...
How radical new collaborations will catalyze a revolution in health.
Center for Extreme Bionics
Carney, Matthew E. “Design and Evaluation of a Reaction-Force Series Elastic Actuator Configurable as Biomimetic Powered Ankle and Knee Prostheses By.” Massachusetts Institute of Technology, 2020.
City Science researchers are developing a slew of tangible and digital platforms dedicated to solving spatial design and urban planning c...
Applied computational biology discoveries vastly expand the range of CRISPR’s access to DNA sequences.
Programmable CRISPR enzymes are powerful and versatile tools for genome editing. They, however, require a specific protospacer adjacent m...
Kevin Esvelt and other experts talk to Axios about the risk of, and potential defenses against, engineered pathogens.
MIT lab offers a model for cost savings, productivity, and safety; principles may also facilitate efficient reopening in the future.
Open Agriculture Initiative (OpenAg)
There are 20 chemokine receptors that bind their respective chemokines. It is not currently understood how these structurally similar rec...
We have significant expertise and motivation to bring problems from the clinic and society into the laboratory to develop novel bioengine...
Biplanar fluoroscopy (BiFlo) enables three-dimensional bone kinematics analysis using x-ray videos and bone geometry from segmented CT. H...
"Our device-driven research is directly inspired by the diseases of our family members and dear friends...indirectly by humanity at large."
Fluorescent probe could allow scientists to watch circuits within the brain and link their activity to specific behaviors.